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Iannis Adamopoulos, a UC Davis researcher which specializes in skeletal and immune-system diseases, has become selected being an Arthritis National Research Foundation (ANRF) Scholar and Sontag Foundation Fellow. Adamopoulos gets a grant of $75,000 to help expand his promising research on rheumatoid arthritis. One of 13 ANRF scholars, he or she is the one awardee being recognized by the Sontag Foundation. ANRF is one of a small number of tax deductible charities specializing in Arthritis Research.

"We are delighted to name Dr. Adamopoulos because the Sontag Foundation Fellow for 2011," said philanthropist and Sontag Foundation President Rick Sontag. "His work may supply the next breakthrough to finally end the debilitating illness that plagued my mother for 37 a few years ended her lifetime." Adamopoulos, a helper professor of internal medicine, found that an immune cytokine referred to as interleukin 23 (IL-23) is often a key regulator of joint inflammation and bone destruction. His finding that abnormal expression of IL-23 causes severe arthritis and bone decrease in mice was recently confirmed in human cells. The next thing in their studies to look for the potential of IL-23 inhibitors as arthritis treatments. "Dr. Adamopoulos is shifting the target of arthritis research and bone health investigations toward immune-system cells not previously recognized as significant," said Timothy Albertson, acting chair with the Department of Internal Medicine at UC Davis. "This change probably will have a profound relation to expanding therapeutic alternatives for those whose arthritis is not managed with current treatments. It's admirable that this ANRF and Sontag Foundation have the insight to identify his innovative work." Before joining UC Davis this year, Adamopoulos conducted drug discovery research at Schering-Plough Biopharma in Palo Alto, Calif. He holds a B.Sc. honors degree through the University of Surrey, an M.Phil. from University College London along with a D.Phil. from the University of Oxford, Wolfson College, where he received a scholarship for research on inflammatory arthritis. Situated in Long Beach, Calif., the ANRF provides research grants to outstanding, early-career scientists who will be becoming leading researchers in rheumatic disease, autoimmunity and inflammation using the goal of finding new treatments for debilitating, chronic diseases. The ANRF's highly competitive, NIH-level review process -- conducted by its Scientific Advisory Board -- helps to ensure that only top-tier applicants and projects are funded. Each year, the Sontag Foundation fully funds the grant of an ANRF-selected researcher who's studying rheumatoid arthritis symptoms. To learn more about ways to make online donations visit curearthritis.org. The [http://chuck598.beeplog.com/blog.pl?blogid=808225 is amongst the nation's leading medical schools, recognized for its research and primary-care programs. The college offers fully accredited master's degree programs in public places health insurance and in informatics, and its combined M.D.-Ph.D. program is training generation x of physician-scientists to conduct high-impact research and translate discoveries into better clinical care. Together with as being a recognized leader in scientific research, the college is devoted to serving under served communities and advancing rural health.